Table 1.

Participant Demographics

Participants (n)	138
Males, n (%)	77 (55.8%)
Baseline Age (years)	71.3 (7.7)
Total PET Scans	476
Scans Per Participant	3.5 (1.2)
Follow-up Time (years)	5.3 (2.0)
Baseline MMSE	28.9 (1.2)
Hypertension, n (%)	67 (48.6%)
Diabetes, n (%)	13 (9.4%)
Obesity (n %, BMI ≥30)	43 (31.2%)
Baseline CRP (mg/L)	4.56 (5.34)
Baseline IL-6 (pg/mL)	3.72 (0.78)
Mean CRP (mg/L)	4.60 (5.58)
Mean IL-6 (pg/mL)	3.99 (1.67)
Rate of change CRP (mg/L/y)	0.17 (0.61)
Rate of change IL-6 (mg/L/y)	0.10 (0.09)

Note: Mean (SD) unless otherwise noted. Baseline values represent the mean of the whole sample of cognitively normal participants (n = 138). Mean and rate of change values were calculated for those with longitudinal imaging measures (>1 PET scan, n = 127). CRP = C-reactive protein; IL-6 = Interleukin-6; MMSE = Mini-Mental State Examination; PET = Positron emission tomography.