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. 2018 Jan 3;73(6):770–778. doi: 10.1093/gerona/glx199

Table 2.

Associations Between Baseline Levels of Inflammatory Markers and Baseline rCBF

Coordinate
Marker Region Side x y z t Value p Value Voxels
CRP Lingual Gyrus (19) R 12 −58 2 −3.36 .001 184
IL-6 Middle Frontal Gyrus(9)* R 42 16 36 −3.15 <.001 176
Postcentral Gyrus (4)* R 40 −16 40 −3.16 .001 69
Lingual Gyrus (18) R 10 −62 4 −3.15 <.001 483
Superior Occipital Gyrus (19)* R 34 −60 42 −3.16 .001 122
Superior Occipital Gyrus (19)* L −26 −74 24 −3.15 <.001 395
Middle Occiptal Cortex (19)* R 24 −86 22 −3.15 <.001 351

Note: Regions where higher levels of CRP and IL-6 were associated lower rCBF. Stereotaxic coordinates are listed, Brodmann areas are indicated in parentheses.

*

indicates regions that did not survive correction for regional tissue volume. CRP = C-reactive protein; IL-6 = Interleukin-6.