Figure 2. VB-1 increases the expression of the signature genes of human DPCs.

(A–F) Dose-dependent effects (0–10 µM) of VB-1 on lef1, wnt5a, bmp2, bmp4, alpl and vcan mRNA expression, in human DPCs cultured for 24 h. Data are shown as the ratio of the respective gene expression to gapdh mRNA expression. Experiments were carried out in triplicates. Data are reported as mean+SEM. Student’s t-test was used to compare data. *P < 0.05, **P < 0.01.