Table 2.
Multivariate analysis, stratified by treatment, of 580 patients (504 with complete covariate information) with lung metastases only for overall survival
| Parameter | Levels |
Hazard ratio (95% CI) |
p‐value |
|---|---|---|---|
| Performance status | PS 0 | 1.00 | <0.001 (df = 2) |
| PS 1 | 1.72 (1.39, 2.13) | ||
| PS 2+ | 5.17 (2.64, 10.1) | ||
| Primary site involved | No | 1.00 | 0.030 (df = 2) |
| Yes | 1.39 (1.08, 1.77) | ||
| Missing | 1.26 (0.89, 1.80) | ||
| Histopathological grade | Grade I | 1.00 | 0.011 (df = 3) |
| Grade II | 1.27 (0.84, 1.90) | ||
| Grade III | 1.72 (1.16, 2.57) | ||
| Missing | 1.39 (0.89, 2.16) | ||
| Time between initial diagnosis | ≤6 months | 1.00 | <0.001 (df = 3) |
| 1–2 years | 1.06 (0.79, 1.41) | ||
| 6–12 months | 1.18 (0.87, 1.61) | ||
| >2 years | 0.57 (0.43, 0.75) | ||
| Size of largest lung lesion | <20 mm | 1.00 | <0.001 (df = 4) |
| 20–30 mm | 1.23 (0.92, 1.65) | ||
| 30–40 mm | 2.17 (1.53, 3.08) | ||
| 40–50 mm | 1.30 (0.90, 1.89) | ||
| ≥50 mm | 2.05 (1.54, 2.73) |