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. 2018 Mar 22;53(5):E12–E14. doi: 10.1002/ppul.23994

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© 2018 The Authors. Pediatric Pulmonology Published by Wiley Periodicals, Inc.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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The C‐terminal sequence of ABCA3 is highly conserved. The predicted protein sequence of c.4938delC starting at p.Met1647 is compared to ABCA3 protein sequences from other vertebrates and other human ABC class A family members. Sequences known to be critical for the function of ABCA1 (Tangier Disease) and ABCA4 (Stargardt Disease) are highlighted. At bottom is the C‐terminal sequence of the Streptomyces peucetius homolog DrrA with a highlighted sequence critical for protein interaction and ATPase activity