Figure 1.

A pictorial “definition” of memory inflation. The definition includes the framing of the phenomenon within the context of antigen persistence and also includes the fact that not all T cells included in the response to a given epitope will have an “inflationary” phenotype. The 2 negatives in the definition (lack of full contraction and lack of exhaustion) could still be improved if a transcriptional programme can be defined more accurately which underpins the distinct phenotypic and functional profile seen