Figure 3.

Antigen presentation and memory inflation. The infection/transduction of a stable cell type which is not a dendritic cell is suggested by different experimental data in MCMV and adenoviral models. Priming requires cross‐presentation and leads to generation of multiple responses to antigens which are not expanded during the memory phase—only those antigens presented on the unconventional APC drive memory inflation. Whether priming can additionally occur on the original APC is not fully defined, but is likely to be much less efficient