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In vitro angiogenesis in response to HGFdf treatment. Representative micrographs of human umbilical cord endothelial cells cultured in basal media and then (A) left untreated, treated with (B) rh-HGF or (C) HGFdf. Treatment with rh-HGF or HGFdf leads to (D) a significant increase in total network length, (E) a significant increase in the number of junctions and branches, (F) a significant increase in branch length, and finally, (G) increased loop perimeter (***p<0.001).
