Table 1. Antibacterial activities of 1 (0.25 μmol) and its C-7 F- and Cl-substituted analogues 1e (0.25 μmol) and 1h (0.25 μmol) against V. cholerae, E. coli and B. subtilis, assessed by disc diffusion agar assay.
Compound | lnhibition zone diameter (mm) |
||
V. cholerae | E. coli | B. subtilis | |
1a | 19 | 38 | 29 |
1e | 19 | 36 | 31 |
1h | 20 | 39 | 31 |