Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Asterisks represent an inactivating mutation in imprinted gene IGF2. In typically developing individuals, IGF2 is expressed only when inherited from the male parent. While the mutation can be inherited from either parent, only individuals who inherit the mutation from their fathers display the disease phenotype. Those who receive the mutated IGF2 allele from their mothers express only the nonmutant copy inherited from their fathers and therefore show typical development.
