Table 5.
Bivariate associations between demographic and other data and delirium development
| Independent variable | Delirium
|
p-value | |
|---|---|---|---|
| No | Yes | ||
| Agea | 62.5 (12.6) | 69.6 (11.9) | 0.020b |
| Sex | 0.202c | ||
| Male | 117 (73.6) | 12 (60.0) | |
| Female | 42 (26.4) | 8 (40.0) | |
| Weighta | 81.0 (17.0) | 81.4 (12.2) | 0.906b |
| Heighta | 170.1 (8.1) | 167.2 (10.4) | 0.230b |
| BMIa | 27.9 (5.2) | 29.2 (4.2) | 0.226b |
| Surgical type of operation | |||
| CABG | 0.032c | ||
| No | 71 (44.7) | 14 (70.0) | |
| Yes | 88 (55.3) | 6 (30.0) | |
| AVR/MVR | 0.267c | ||
| No | 117 (73.6) | 17 (85.0) | |
| Yes | 42 (26.4) | 3 (15.0) | |
| Bentall ± ascending aorta ± arch replacement | 0.746c | ||
| No | 148 (93.1) | 19 (95.0) | |
| Yes | 11 (6.9) | 1 (5.0) | |
| AVR and MVR (± CABG) | <0.001c | ||
| No | 146 (91.8) | 10 (50.0) | |
| Yes | 13 (8.2) | 10 (50.0) | |
| ASD/VSD | 0.549c | ||
| No | 154 (96.9) | 20 (100.0) | |
| Yes | 5 (3.1) | 0 (0.0) | |
| Transfer to HDU | 0.321c | ||
| No | 139 (87.4) | 19 (95.0) | |
| Yes | 20 (12.6) | 1 (5.0) | |
| EuroSCORE IIa,d | 1.7 (2.6)/3.7 (5.9) | 3.7 (5.3)/6.3 (6.6) | 0.001e |
| CPB (min)a | 118.8 (40.2) | 140.2 (56.0) | 0.113b |
| Ischemia time during CPB (min)a | 75.8 (29.7) | 90.1 (42.0) | 0.155b |
| In-hospital LOS (days)d | 7.0 (2.0) | 7.5 (3.5) | 0.028f |
| ICU LOS (hours)d | 26.0 (19.0) | 45.5 (31.2) | <0.001f |
| Total sedation time (hours)d | 5.0 (3.0) | 6.2 (6.6) | 0.189f |
| LOS with endotracheal tube (hours)d | 8.0 (4.0) | 11.5 (10.6) | 0.001f |
| NL ratio, 2nd postoperative dayd | 9.2 (7.3) | 16.4 (17.9) | 0.001f |
| Urea operation dayd | 41.0 (19.0) | 49.5 (29.0) | 0.025f |
| Urea 2nd postoperative dayd | 40.0 (25.0) | 52.5 (45.5) | 0.016f |
| Creatinine operation dayd | 1.0 (0.3) | 1.1 (0.5) | 0.018f |
| Creatinine 1st postoperative dayd | 1.0 (0.5) | 1.3 (0.5) | 0.006f |
| Creatinine 2nd postoperative dayd | 1.0 (0.5) | 1.3 (0.5) | 0.026f |
| Sodium 1st postoperative day3 | 142.7 (3.6) | 144.5 (3.4) | 0.039b |
| Sodium 2nd postoperative daya | 141.2 (3.7) | 143.4 (4.0) | 0.033b |
| PT operation daya | 13.1 (1.3) | 14.4 (2.4) | <0.001b |
| INR operation daya | 1.0 (0.1) | 1.2 (0.2) | <0.001b |
Notes:
a
Mean (standard deviation),
b
2-sided t-test,
c
χ2,
d
median (interquartile range),
e
Monte-Carlo test,
f
Mann–Whitney test. Bold data are statistically significant.
Abbreviations: ASD, atrial septal defect; AVR, aortic valve replacement; BMI, body mass index; CABG, coronary artery bypass grafting; CPB, cardiopulmonary bypass; HDU, high-dependency unit; ICU, intensive care unit; INR, International Normalized Ratio; LOS, length of stay; MVR, mitral valve replacement; NL, neutrophil-to-lymphocyte; PT, prothrombin time; VSD, ventricular septal defect.