Figure 3.

Exploration of positional cues increases Arc mRNA expression in the proximal CA3 region. The distal CA3 region and dentate gyrus are unaffected. Arc mRNA expression was significantly in the proximal CA3 region following exposure to positional cues (b) but not in the distal CA3 region (a) or lower (c) and upper (d) blades of the dentate gyrus. One way ANOVA: **p < .01. (e–h) Photomicrographs show Arc mRNA expression (red points, indicated by arrows) in the CA3 regions and the dentate gyrus of control animals (control) or animals that participated in positional cue exploration (test). Blue: nuclear staining with DAPI. Images were taken using a 63× objective. Scale bar: 10 μm [Color figure can be viewed at http://wileyonlinelibrary.com]