Table 4.

Optical coherence tomography (OCT) results

OCT parameters assessed by reading centre (neurosensory retina + subretinal fluid)	Combination n/N = 48/85	Laser n/N = 26/43	p‐value†
Foveal centre point thickness [μm (SD)]
Baseline
Mean (SD)	405.0 (152.1)	450.9 (157.9)	0.139
Mean change from baseline
Month 4	−134.5 (153.9)	−31.4 (109.5)	0.003*
Month 12	−111.6 (152.5)	−59.3 (108.2)	0.068
Central subfield mean thickness [μm (SD)]
Baseline
Mean	421.5 (130.1)	470.1 (123.6)	0.061
Mean change from baseline
Month 4	−118.7 (130.9)	−41.5 (86.1)	0.007*
Month 12	−96.7 (120.9)	−54.0 (89.9)	0.062
Total volume within 6 mm ETDRS grid, [mm³ (SD)]
Baseline
Mean	9.6 (1.9)	10.2 (2.0)	0.204
Mean change from baseline
Month 4	−1.4 (1.4)	−0.4 (0.8)	0.001*
Month 12	−1.2 (1.1)	−0.5 (1.0)	0.004*

ETDRS = Early treatment diabetic retinopathy study, SD = standard deviation. ^†Paired t‐test p‐value, significance level *p < 0.05.