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a) Correlation analysis comparing fragment reactivity with glutathione (k GSH) to average fragment reactivity across seven Cdk2 mutants (k̄ protein). b) Distribution of rate enhancement factors for the covalent fragment library screened against Cdk2(WT). c) DMSO‐Normalized fluorescence data from qIT assay for acrylamide 1 (0.5 mm) in reaction with Cdk2(WT) or glutathione (5 μm) (n=2).
