Table 1. The main automated crystallographic pipelines distributed by CCP4.

Pipeline	Description	Use of databases	Expected CPU time
xia2	Data processing	0	Minutes to hours
BALBES	Molecular replacement	3 GB	Hours to days
MoRDa	Molecular replacement	3 GB	Hours to days
MrBUMP	Molecular replacement	26 GB	Hours to days
AMPLE	Ab initio modelling and molecular replacement	ROSETTA	Days to weeks
SIMBAD	Contaminant searches and sequence-less MR	25 GB	Hours to days
CRANK2	Experimental phasing (SAD, SIRAS, MAD)	0	Hours to days
ARCIMBOLDO	Fragment-based MR	∼1 GB	Hours to weeks
Phaser	Automated phasing	0	Minutes to weeks
Buccaneer	Model building	0	Minutes to hours
Nautilus	DNA/RNA model building	0	Minutes to hours