Figure 5.
Upregulation of Yy1 parallels Xist.
Notes: (A) Relative expression of Yy1 in female C57BL/6 mice injected with CFA or saline (n=3–4). (B) Relative expression of YY1 in CRPS patients receiving ketamine therapy, responders n=7, poor responders n=6. Expression of Yy1/YY1 normalized to Gapdh/GAPDH. One-way ANOVA and Student’s t-test were used for statistical analysis *p<0.05, **p<0.01. Data represent mean ± SEM.
Abbreviations: ANOVA, analysis of variance; CFA, complete Freund’s adjuvant; CRPS, complex regional pain syndrome; SEM, standard error of the mean; Xist, X-inactive-specific transcript; YY1, Yin-Yang 1.