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. Author manuscript; available in PMC: 2018 May 11.
Published in final edited form as: Curr Alzheimer Res. 2014;11(6):608–622. doi: 10.2174/1567205010666131212113218

Figure 5.

Figure 5

Effect of pharmacological inhibitor (1) and (3) on Aβ-induced expression of IL-1β and TNF-α mRNA in THP-1 cells. THP-1 cells pre-incubated with 10 µM nicotine (Nic) or mecamylamine (Mec) for 30 min, were then treated with compound (1) and (3) (both 10 µM) for 24 h. After an additional 24 h of incubation with Aβ, levels of mRNA expression relative to that 18S, used as an internal control, were evaluated. Data are expressed as the mean and standard deviation of two independent experiments.

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