Table 4.

Mean ± standard deviation of inflammatory cytokine production in PBMCs from patients with Alzheimer’s disease (AD) and healthy control (HC) subjects.

Variable	HC (n=20)		AD (n=20)		p-value
	Basal	Aβ	Basal	Aβ	+ Aβ	# group	† interaction
IL-1β (pg/ml)	60.2±23.1	418.4±212.4	175.9±90.7	1127.4±261.8	<0.001	<0.001	<0.001
MCP-1 (pg/ml)	24.5±5.6	58.9±14.5	56.9±21.6	143.4±38.3	<0.001	<0.001	<0.001
TNF-α (pg/ml)	82.7±29.8	350.4±167.2	124.4±35.9	649.9±257.0	<0.001	<0.001	<0.001
IL-6 (pg/ml)	277.7±139.7	2037.5±687.6	726.1±213.7	2953.5±868.9	<0.001	<0.001	0.056

Probability that effect on the addressed variable is influenced by:

⁺Aβ, for each variable, the differences have been tested between the means of basal production of the two groups and the means of the Aβ-induced production of the two groups;

^#groups, for each variable, the differences have been tested between the means of HC group in two conditions (basal and Aβ) and the means of the AD group in two conditions (basal and Aβ);

^†probability that the effects are greater in one distinct group (interaction Aβ*group).