Table 5.

Mean ± standard deviation of IL-1β, MCP-1, TNF-α and IL-10 production in THP-1 cells pre-incubated with LY294002, PD98059 or SB202190 and then incubated in the presence of Aβ for 24 h

	IL-1β	MCP-1	TNF-α	IL-10
Aβ	0.74±0.06	0.77±0.02	0.84±0.06	0.82±0.06
Aβ+LY294002	0.52±0.11*	0.49±0.11*	0.94±0.01	0.71±0.05
Aβ+PD98059	0.33±0.01*	0.50±0.01*	0.81±0.02	1.03±0.05*
Aβ+SB202190	0.47±0.18*	0.80±0.10	0.42±0.01*	0.93±0.12
p-valuea	0.004	0.010	0.005	0.008

^aKruskal-Wallis H test.

^*p<0.05 post hoc test vs. Aβ