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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Curr Opin Pediatr. 2018 Apr;30(2):285–291. doi: 10.1097/MOP.0000000000000601

Figure 1. Organization of Environmental Indicators.

Figure 1

Known and unknown toxicants interact with nutrition and social stressors to elicit a biological response via multiple physiologic pathways. This response depends on the life stage at which exposure occurs. The Targeted Resource will provide validated markers of exposure to known toxicants, nutrients, and stress markers. The Untargeted Resource will undertake exposomic analyses to assess a wide range of unknown chemical signatures that include environmental chemicals, their breakdown products, and biomolecular signatures of disrupted cellular function.