Fig. 2.
Overall view of the human primosome. p58C with an adjacent linker and the rest of the molecule are represented as cartoon and surface, respectively. [4Fe–4S] is represented as ball-sticks, with iron and sulfur colored red and yellow, respectively. The inset shows close-up view of [4Fe–4S]2+ coordination by four conservative Cys of p58C. Coordinates of the human primosome (PDB ID 5EXR) were used to draw this structure. All structural figures are prepared using the PyMOL Molecular Graphics System (version 1.8, Schrödinger, LLC).