Table 1.

Inhibition of recombinant human MAO-A and MAO-B by H. afrum and C. villosus fractions, subfractions and pure constituents

Samples	MAO-A	MAO-B
	IC50 value	IC50 value
EtOAc fraction (H. afrum)#	3.37 ± 0.03	13.50 ± 0.71
EtOAc fraction (C. villosus)#	5.62 ± 0.11	1.87 ± 0.03
Subfraction F-1 (H. afrum)#	16.56 ± 0.85	1.93 ± 0.21
Subfraction F-2 (H. afrum)#	6.18 ± 0.62	3.05 ± 0.15
Subfraction F-3 (H. afrum)#	2.17 ± 0.01	4.12 ± 0.59
Subfraction F-4 (H. afrum)#	9.49 ± 0.15	18.41 ± 0.33
Subfraction Fr-1 (C. villosus)#	0.80 ± 0.05	0.15 ± 0.014
Subfraction Fr-2 (C. villosus)#	2.47 ± 0.26	1.19 ± 0.03
Subfraction Fr-3(C. villosus)#	7.22 ± 1.44	11.53 ± 1.95
Quercetin*	1.52 ± 0.09	28.39 ± 5.41
Myricetin*	9.93 ± 0.63	59.34 ± 1.78
Genistein*	2.74 ± 0.01	0.65 ± 0.11
Chrysin*	0.25 ± 0.04	1.04 ± 0.17
Phenelzine*a	0.27 ± 0.03	0.14 ± 0.02
Clorgyline*b	0.007 ± 0.0005	----
Deprenyl*c	----	0.05 ± 0.01

^aPositive control for both MAO enzyme;

^bPositive control selective for MAO-A;

^cselective for MAO-B.

^*Shows inhibition = μM and

^#shows inhibition = (μg/ml)