. Author manuscript; available in PMC: 2018 May 11.

Published in final edited form as: J Drug Target. 2015 Sep 22;24(6):503–507. doi: 10.3109/1061186X.2015.1087529

Table 1.

Solubility of PTTC in various solvents.

Solvent	Solubility (mg/ml)	FDA IIG
Dimethyl sulfoxide	74.44 ± 1.39	Yes
Ethyl pyruvate	21.37 ± 1.44	No
Capric triglyceride	6.49 ± 1.67	Yes
Propylene carbonate	4.06 ± 0.23	Yes
Triacetin	2.49 ± 0.79	Yes
Isoamyl alcohol	2.31 ± 0.56	No
Ethanol	1.66 ± 0.14	Yes
N-Butanol	0.87 ± 0.14	No

Solubility of PTTC was determined in a series of solvents. The drug had greatest solubility in dimethyl sulfoxide and ethyl pyruvate. All values represent mean ± standard deviation.