Fig. 2.

Association between birthweight and type 2 diabetes risk later in life (a) and the potential mediating factors (b). In (a), women with a birthweight of 3.63–4.54 kg served as the reference group. Logistic regression model was adjusted for cigarette smoking, alcohol consumption, physical activity, dietary fibre intake, dietary glycaemic load, BMI and family history of diabetes. Error bars indicate 95% CIs. In (b), the area of each circle is proportional to the percentage of the total effect that was mediated by that particular biomarker. Overlapping among circles represents potential interactions between these mediating factors. SBP, systolic blood pressure