Table 1.
The relationship between clinical histopathological features of OLK and expression of PRC1
| Factors | Number (n) | Positive rate | Intensity | Staining score | p value |
|---|---|---|---|---|---|
| Sex | |||||
| Male | 14 | 53.43 ± 13.74 | 2.21 ± 0.58 | 111.93 ± 13.25 | 0.422 |
| Female | 10 | 52.80 ± 11.08 | 2.20 ± 0.42 | 116.80 ± 15.89 | |
| Age (years) | |||||
| ≤60 | 16 | 54.31 ± 13.85 | 2.19 ± 0.54 | 115.19 ± 15.18 | 0.563 |
| >60 | 8 | 50.88 ± 9.45 | 2.25 ± 0.46 | 111.50 ± 12.91 | |
| Location | |||||
| Buccal | 8 | 53.5 ± 17.07 | 2.13 ± 0.64 | 110.25 ± 18.28 | 0.627 |
| Tongue | 10 | 51.50 ± 3.49 | 2.30 ± 0.48 | 114.60 ± 13.60 | |
| Others | 6 | 55.50 ± 8.55 | 2.17 ± 0.41 | 117.83 ± 9.85 | |
| Dysplasia | |||||
| Without | 5 | 57.60 ± 19.32 | 1.80 ± 0.45 | 96.80 ± 4.60 | 0.000*** |
| Mild | 7 | 48.57 ± 8.83 | 2.29 ± 0.49 | 107.71 ± 8.28 | |
| Moderate | 6 | 55.67 ± 7.66 | 2.17 ± 0.41 | 118.17 ± 5.81 | |
| Severe | 6 | 52.33 ± 14.29 | 2.50 ± 0.55 | 131.33 ± 8.55 |
Expression of PRC1 in OLK was not relevant to their sex, age, and location of lesions (p > 0.05) while exhibited a positive correlation with the degree of epithelial dysplasia (p = 0.000). Error bars, mean ± SD (n ≥ 5); ***p < 0.001; t-test or Wilcoxon rank sum test.