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. 2018 May 11;9(5):571. doi: 10.1038/s41419-018-0632-8

Fig. 6. Effects of IDN-6556 on the centriolar SAS-6 levels in cells undergoing apoptosis.

Fig. 6

HeLa cells were treated with thymidine for 24 h, released into a fresh medium with MG132 and IDN-6566, and cultured for 8 or 12 h. The cells were immunostained with the SAS-6 (green) antibody. DNA was visualized with DAPI (blue). Scale bar, 10 μm. The centriolar intensity of SAS-6 was measured and analyzed with a scatter plot. Greater than 100 centrosomes per experimental group were analyzed in two independent experiments. *P < 0.05