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. 2017 Jul 12;55(6):4612–4623. doi: 10.1007/s12035-017-0646-8

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — The effect of Aβ oligomers on PC12 cells viability. The effect of oligomeric Aβ42 or scrambled Aβ at 1 μM concentration on PC12 cell viability after 24-h treatment (a). Thioflavin (ThT) fluorescence analysis of the Aβ42 scrambled and Aβ42 in oligomeric form (b). Proteins were subjected to denaturing SDS–PAGE followed by silver staining. Electrophoretic analysis of the Aβ42 scrambled and Aβ42 in oligomeric form (AβO) (c). For statistical comparison, Student’s t test or one-way analysis of variance (ANOVA) with Neuman-Keuls post hoc test was used. P values <0.05 were considered statistically significant (***−p < 0.001)