Table 2.
Caudate | Putamen | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Seed no. | Ventral inferior | Ventral superior | Dorsal | Dorsal caudal | Dorsal rostral | Ventral rostral | ||||||
Genotype groups | Met-carriers | Val/Val | Met-carriers | Val/Val | Met-carriers | Val/Val | Met-carriers | Val/Val | Met-carriers | Val/Val | Met-carriers | Val/Val |
MMSE | 0.11 | 0.21* | 0.20 | 0.23* | 0.03 | 0.19 | 0.23* | 0.14 | 0.23* | 0.17 | 0.28* | 0.25* |
CASI total scores | 0.11 | 0.20* | 0.19 | 0.21* | 0.02 | 0.18 | 0.21* | 0.11 | 0.19 | 0.13 | 0.23* | 0.22* |
Executive function test | 0.11 | 0.21* | 0.19 | 0.21* | 0.02 | 0.18 | 0.20 | 0.12 | 0.19 | 0.14 | 0.23* | 0.21* |
Mental Manipulation | −0.07 | 0.12 | 0.06 | 0.24* | −0.02 | 0.22* | 0.15 | 0.14 | 0.15 | 0.16 | 0.13 | 0.22* |
Attention | 0.19 | 0.23* | 0.27** | 0.26** | 0.12 | 0.14 | 0.17 | 0.23* | 0.19 | 0.22* | 0.23* | 0.29** |
Orientation | 0.10 | 0.18 | 0.12 | 0.10 | −0.04 | 0.05 | 0.09 | 0.10 | 0.08 | 0.09 | 0.15 | 0.14 |
Long-term memory | 0.22* | −0.01 | 0.26* | 0.13 | 0.14 | 0.12 | 0.29** | 0.03 | 0.23* | 0.07 | 0.24* | 0.17 |
Short-term memory | 0.11 | 0.29** | 0.10 | 0.18 | −0.14 | 0.15 | 0.08 | 0.10 | 0.03 | 0.09 | 0.11 | 0.15 |
Abstract thinking | 0.09 | 0.18 | 0.15 | 0.10 | −0.01 | 0.11 | 0.15 | 0.03 | 0.14 | 0.03 | 0.17 | 0.03 |
Drawing | −0.03 | 0.13 | 0.13 | 0.15 | 0.10 | 0.18 | 0.20 | 0.04 | 0.20 | 0.12 | 0.25* | 0.16 |
Verbal fluency | 0.11 | 0.14 | 0.22* | 0.20* | 0.06 | 0.12 | 0.22 | 0.08 | 0.24* | 0.09 | 0.23* | 0.17 |
Language | 0.12 | 0.18 | 0.16 | 0.25* | 0.11 | 0.23* | 0.20 | 0.13 | 0.19 | 0.17 | 0.20 | 0.25* |
NPI total scores | −0.04 | 0.06 | 0.02 | −0.05 | 0.08 | −0.01 | −0.05 | −0.03 | 0.00 | −0.04 | −0.03 | 0.02 |
Delusion | −0.14 | −0.06 | 0.00 | 0.00 | 0.00 | 0.08 | −0.08 | 0.06 | −0.06 | 0.07 | −0.07 | 0.04 |
Hallucination | −0.05 | −0.14 | −0.07 | −0.21* | −0.12 | −0.20* | −0.16 | −0.27** | −0.16 | −0.28** | −0.13 | −0.22* |
Aggression | −0.16 | −0.04 | −0.10 | −0.02 | −0.02 | 0.01 | −0.09 | −0.15 | −0.03 | −0.16 | −0.12 | −0.08 |
Depression | 0.10 | 0.16 | 0.07 | 0.00 | 0.06 | 0.13 | 0.08 | 0.14 | 0.05 | 0.14 | 0.01 | 0.22* |
Anxiety | 0.04 | 0.21* | 0.05 | −0.01 | 0.00 | 0.08 | 0.05 | 0.02 | 0.00 | 0.09 | −0.03 | 0.10 |
Elation | −0.09 | −0.12 | −0.17 | −0.15 | −0.04 | −0.04 | −0.16 | −0.04 | −0.04 | −0.01 | −0.11 | −0.02 |
Apathy | −0.06 | −0.22* | −0.10 | −0.02 | 0.01 | −0.07 | −0.16 | 0.10 | −0.09 | 0.03 | −0.12 | 0.07 |
Disinhibition | −0.20 | −0.02 | −0.02 | −0.12 | −0.01 | −0.03 | −0.06 | −0.05 | −0.01 | −0.08 | 0.01 | −0.05 |
Irritability | −0.07 | 0.23* | 0.02 | 0.11 | 0.00 | 0.07 | −0.05 | −0.09 | −0.04 | 0.02 | −0.06 | 0.13 |
Aberrant motor behavior | −0.14 | −0.11 | −0.07 | −0.10 | −0.05 | −0.08 | −0.20 | −0.02 | −0.15 | −0.04 | −0.15 | −0.02 |
Sleep disorder | 0.12 | 0.15 | 0.13 | 0.00 | 0.23* | 0.02 | 0.16 | −0.01 | 0.21* | −0.02 | 0.22* | −0.07 |
Eating behavior | 0.04 | −0.07 | 0.09 | −0.09 | 0.06 | −0.24* | −0.03 | −0.27** | −0.06 | −0.31** | 0.03 | −0.24* |
MMSE Mini-Mental State Examination, NPI neuropsychiatric inventory, CASI cognitive ability screening instrument
Numbers indicate Pearson’s correlation coefficients—*p < 0.05; **p < 0.01