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. 2017 Jul 13;55(6):4637–4649. doi: 10.1007/s12035-017-0668-2

Table 4.

Significant correlations between peak cluster volume and neurobehavioral test scores in the Valine homozygotes

Seed PCC DCP seed DRP seed
Peak cluster Superior medial frontal Superior occipital Middle occipital Superior parietal Postcentral Caudate Angular Middle occipital Paracentral lobule Caudate SMA Postcentral
CASI EFT scores −0.05 0.15 0.12 0.20* 0.09 −0.05 0.05 0.08 −0.12 0.13 −0.05 0.05
Abstract thinking 0.10 0.19 0.05 0.15 0.15 −0.10 0.07 0.03 −0.10 0.20* 0.07 0.13
Hallucination 0.04 0.02 0.06 0.19** 0.11 −0.05 −0.03 0.09 0.21* 0.05 0.00 −0.13
Aggression 0.18 0.20* 0.20* −0.01 0.06 0.12 0.24* 0.26** 0.13 0.00 0.25* 0.08
Depression 0.11 0.09 0.04 0.03 0.20* −0.03 0.16 0.04 0.06 0.17 0.12 0.27**
Elation −0.02 −0.24* −0.26** −0.12 −0.06 −0.07 −0.24* −0.24* −0.17 −0.06 −0.12 −0.10

The CASI seed regions are dorsal rostral putamen (DRP) and dorsal caudal putamen (DCP)

MMSE Mini-Mental State Examination, EFT executive function test, CASI cognitive ability screening instrument, PCC posterior cingulate cortex, SMA supplementary motor area

Numbers indicate Pearson’s correlation coefficients—*p < 0.05; **p < 0.01