Table 6.

Comparison of the LILRB and KIR2DL4 polymorphisms in women depending on the severity of endometriosis

Genotype	E I + II (%)	E III + IV (%)	E III + IV vs E I + II
			P	OR	95% CI	Test for independence		Test for trend
						p	χ2	p	χ2
LILRB1 rs41308748:G>A	N = 16	N = 183
GG*	13 (81.25)	150 (81.97)		1		0.43	1.70	0.68	0.17
GA	3 (18.75)	21 (11.48)	0.44	0.61	(0.16–2.31)
AA	0 (0.00)	12 (6.55)	0.60	2.24	(0.13–40.02)
Minor allele A	3 (9.38)	45 (12.30)
LILRB1 rs1061680:T>C	N = 16	N = 183
TT*	12 (75.00)	122 (66.67)		1		0.63	0.93	0.38	0.76
TC	4 (25.00)	53 (28.96)	0.78	1.30	(0.40–4.23)
CC	0 (0.00)	8 (4.37)	1.00	1.74	(0.09–31.90)
Minor allele C	4 (12.5)	69 (18.85)
LILRB2 rs383369:G>A	N = 16	N = 183
AA*	15 (93.75)	124 (67.76)		1		0.06	5.49	0.024	5.10
AG	1 (6.25)	58 (31.69)	0.043 a	7.02	(0.90–54.43)
GG	0 (0.00)	1 (0.55)	1.00	0.37	(0.01–9.58)
Minor allele G	1 (3.13)	60 (16.39)
LILRB2 rs7247538:C>T	N = 16	N = 183
TT*	6 (37.50)	64 (34.97)		1		0.51	1.34	0.69	0.16
CT	6 (37.50)	91 (49.73)	0.56	1.42	(0.44–4.61)
CC	4 (25.00)	28 (15.30)	0.72	0.66	(0.17–2.51)
Minor allele C	14 (43.75)	147 (40.16)
KIR2DL4 rs649216:T>C	N = 16	N = 187
TT*	6 (37.50)	60 (32.09)		1		0.23	2.95	0.62	0.25
CT	4 (25.00)	85 (45.45)	0.33	2.13	(0.57–7.86)
CC	6 (37.50)	42 (22.46)	0.56	0.70	(0.21–2.32)
Minor allele C	16 (50.00)	169 (45.19)

P probability, OR odds ratio, 95% CI 95% confidence interval from two-sided Fisher’s exact test, χ ² _df = 2 p Chi-square test for independence with two degrees of freedom for all tested polymorphisms, χ ² _df = 1 p Chi-square test for trend with one degree of freedom for all tested polymorphisms; *Reference; for four samples from the III + IV endometriosis group we could not perform LILRB1 and LILRB2 genotyping because of a lack of DNA

^a P _corr. = 0.215