Table 2.
Baseline cytometric characteristic of patients responding and not responding to anti-TNFα treatment
| Responding group (n = 10) |
Non-responding group (n = 10) |
Non-paired T test p value |
|
|---|---|---|---|
| Intracellular cytokines | |||
| CD4 IL-17A | 0.2 ± 0.05 | 0.2 ± 0.05 | 0.98 |
| CD4 IL-4 | 0.2 ± 0.07 | 0.5 ± 0.1 | 0.08 |
| CD4 IFNγ | 6.6 ± 1.4 | 6.3 ± 1.3 | 0.9 |
| CD4 TNFα | 26.9 ± 4.1 | 32.0 ± 6.1 | 0.5 |
| CD8 IFNγ | 19.5 ± 2.5 | 26.7 ± 5.4 | 0.3 |
| CD8 TNFα | 20.8 ± 2.9 | 40.7 ± 8.2 | 0.04 |
| Activation markers | |||
| CD4 CD28 null | 2.6 ± 1.0 | 5.5 ± 2.3 | 0.5 |
| CD4 CD25 | 38.8 ± 1.5 | 38.1 ± 4.2 | 0.6 |
| CD4 CD69 | 4.3 ± 1.5 | 2.0 ± 0.6 | 0.2 |
| CD8 CD28 null | 26.0 ± 4.1 | 36.3 ± 6.5 | 0.2 |
| CD8 CD25 | 7.5 ± 1.2 | 13.8 ± 4.8 | 0.6 |
| CD8 CD69 | 5.5 ± 1.7 | 4.3 ± 1.8 | 0.7 |
Data are shown as mean percentage of cells ± SEM