Table 1.
The correlation between MLL2 expression and clinicopathological characteristics of Kazakh ESCC patients
| Characteristics | n | MLL2 expression | χ2 | P | |
|---|---|---|---|---|---|
| High (%) | Low (%) | ||||
| Specimen | 16.465 | < 0.001* | |||
| Adjacent normal tissue | 67 | 8 (11.9) | 59 (88.1) | ||
| ESCC | 67 | 29 (43.3) | 38 (56.7) | ||
| Gender | 0.448 | 0.348 | |||
| Female | 19 | 7 (36.8) | 12 (63.2) | ||
| Male | 48 | 22 (45.8) | 26 (54.2) | ||
| Age (years) | 2.417 | 0.095 | |||
| > 60 | 35 | 12 (34.3) | 23 (65.7) | ||
| ≤ 60 | 32 | 17 (53.1) | 15 (46.9) | ||
| TNM stage | 4.424 | 0.037* | |||
| I–II | 54 | 20 (37.0) | 34 (63.0) | ||
| III | 13 | 9 (69.2) | 4 (30.8) | ||
| T classification | 1.123 | 0.209 | |||
| T1–T2 | 28 | 10 (35.7) | 18 (64.3) | ||
| T3–T4 | 39 | 19 (48.7) | 20 (51.3) | ||
| N classification | 0.781 | 0.264 | |||
| No | 41 | 16 (39.0) | 25 (61.0) | ||
| Yes | 26 | 13 (50.0) | 13 (50.0) | ||
| Differentiation | 4.447 | 0.032* | |||
| Well | 18 | 4 (22.2) | 14 (77.8) | ||
| Moderately/poorly | 49 | 25 (51.0) | 24 (49.0) | ||
| Tumor size | 4.195 | 0.035* | |||
| < 4 | 35 | 11 (31.4) | 24 (68.6) | ||
| ≥ 4 | 32 | 18 (56.3) | 14 (43.8) | ||
| Vascular invasion | 2.2 | 0.118 | |||
| Negative | 52 | 20 (38.5) | 32 (61.5) | ||
| Positive | 15 | 9 (60.0) | 6 (40.0) | ||
*Statistically significant (P < 0.05); n number of cases; MLL2 Expression cases (Ratio); Χ2 Chi-square value