Table 5.
Univariate analysis of possible predictors for post-operative infections following radical gastrectomy for gastric cancer after matching (n = 722)
| Variables | Infections (n = 68) | Non-infection (n = 654) | χ2 value | P value |
|---|---|---|---|---|
| Sex (male: female) | 48/20 | 406/248 | 1.911 | 0.167 |
| Age (years) ≥ 65/<65 | 20/48 | 158/496 | 0.915 | 0.339 |
| BMI (kg/m2) ≥ 25/<25 | 13/55 | 60/594 | 6.701 | 0.010 |
| Smoking history; yes/no | 34/34 | 227/427 | 6.239 | 0.012 |
| ASA score ≥ 3/<3 | 16/52 | 123/531 | 0.883 | 0.347 |
| Comorbidity; yes/no | 28/40 | 206/448 | 2.634 | 0.105 |
| Pre-operative white blood cell count (× 109/L) ≥ 4/<4 | 64/4 | 584/70 | 1.556 | 0.212 |
| Pre-operative lymphocyte count (× 109/L) ≥ 1.5/<1.5 | 38/30 | 353/301 | 0.090 | 0.764 |
| Pre-operative hemoglobin (g/L) ≥ 100/<100 | 43/25 | 389/265 | 0.361 | 0.548 |
| Pre-operative albumin (g/L) ≥ 35/ <35 | 39/29 | 429/225 | 1.836 | 0.175 |
| Complication due to the tumora; yes/no | 28/40 | 266/388 | 0.006 | 0.936 |
| Neo-adjuvant chemotherapy; yes/no | 4/64 | 38/616 | 0.001 | 0.981 |
| Operation method; open/laparoscopy | 7/61 | 58/596 | 0.153 | 0.696 |
| Extent of gastric resection; subtotal/total | 48/20 | 487/167 | 0.482 | 0.487 |
| Combined multi-organ resection; yes/no | 22/46 | 80/574 | 20.555 | < 0.001 |
| Splenectomy; yes/no | 5/63 | 11/643 | 0.141 | 0.002 |
| Operation time (min) ≥ 240/< 240 | 36/32 | 183/471 | 18.159 | < 0.001 |
| Intra-operative blood loss (mL) ≥ 300/<300 | 26/42 | 191/463 | 2.389 | 0.122 |
| Tumor size (cm) ≥ 5/<5 | 39/29 | 343/311 | 0.595 | 0.440 |
| Depth of invasion; T4/T1–3 | 55/13 | 489/165 | 1.239 | 0.266 |
| Lymph node metastasis; positive/negative | 48/20 | 469/185 | 0.038 | 0.845 |
| pTNM stage; III/I–II | 49/19 | 433/221 | 0.950 | 0.330 |
| Peri-operative BTF; yes/no | 43/25 | 318/336 | 5.260 | 0.022 |
BMI body mass index, ASA American Society of Anesthesiologist, BTF blood transfusion
aIncluding pyloric obstruction or bleeding