Table 2.
Characteristics of responders versus nonresponders (women lost to follow-up)
| Responders (n 127) | Lost to follow-up (n 63) | Difference (95% CI) | |
|---|---|---|---|
| Age at time of surgery (years) | 61.6 ± 9.7 | 67.7 ± 10.4 | −6.1* (−9.2, −3.1) |
| Parity | 2 (1–6) | 3 (0–5) | 0 (0, 1.0) |
| BMI (kg/m2) | 26.6 ± 4.2 | 26.9 ± 4.1 | −0.3 (−1.6, 1.1) |
| Prior number of POP surgeries | 1 (1–3) | 1 (1–2) | 0 (0, 0) |
| Prior number of treated vaginal compartments | 2 (1–3) | 2 (1–3) | 0 (0, 0) |
| POP-Q stage at time of surgery | |||
| • Stage II | 69 (54.3) | 21 (33.3) | 21.0* (6.5, 35.5) |
| • Stage III | 55 (43.3) | 42 (66.7) | −23.4* (−37.8, −8.9) |
| • Stage IV | 3 (2.4) | 0 | 2.4 (−0.3, 5.0) |
| Pain at baseline | |||
| • Yes | 61/113 (54.0) | 23/48 (47.9) | 6.1 (−10.8, 22.9) |
| • UDI pain score | 28.7 (26.9, 30.4) | 23.4 (19.8, 27.0) | 5.3 (−3.7, 14.3) |
| Dyspareunia at baseline | |||
| • Moderately to quite a bit | 26/111 (23.4) | 3/45 (6.7) | 16.8* (6.0, 27.5) |
| • Yes | 45/111 (40.5) | 4/45 (8.9) | 31.7* (19.3, 44.0) |
| Outcomes at 1-year follow-up | |||
| Composite success | 83/111 (74.8) | 31/43 (72.1) | 2.6 (−12.9, 18.3) |
| Overall POP-Q ≥ stage II | 66/115 (57.4) | 23/52 (44.2) | 13.2 (−3.1, 29.4) |
| PGI-I (much to very much better) | 78/108 (72.2) | 31/49 (63.3) | 8.9 (−6.9, 24.9) |
| VAS EQ-5D | 78.2 ± 14.6 | 72.4 ± 20.3 | 5.8* (0.2, 11.5) |
| Exposure | 9/114 (7.9) | 5/52 (9.6) | −1.7 (−11.1, 7.7) |
| UDI pain score | 14.3 (13.1, 15.5) | 13.8 (10.4, 17.1) | 0.5 (−6.9, 7.9) |
| Dyspareunia | |||
| • Moderately to quite a bit | 18/115 (16.2) | 3/47 (4.7) | 9.3 (−0.4, 18.9) |
| • Yes | 35/115 (30.4) | 8/46 (17.4) | 13.0 (−0.8, 26.9) |
Data presented as mean ± standard deviation (SD), median (range), n (%), or mean (95% CI)
BMI body mass index, PGI-I Patient Global Impression of Improvement, VAS EQ-5D perceived health condition according visual analog scale, EuroQuol-5D questionnaire (100 = best imaginable, 0 = worst imaginable), UDI pain score urodynamic pain score, 0–100, CI confidence interval
*This difference would be statistically significant if tested at a significance level of 0.05