Table 6.
Changes in health-related quality of life and sexual function between baseline and 7 years
| Mesh (n 66) | Native tissue (n 76) | Difference (95% CI) | ||
|---|---|---|---|---|
| Mean change in UDI domain scores | ||||
| UDI | Overactive bladder | −6.3 ± 25.0 | −3.4 ± 27.5 | 2.9 (−6.8, 12.6) |
| Incontinence | 3.3 ± 26.0 | 1.3 ± 27.0 | −2.0 (−11.5, 7.5) | |
| Obstructive micturition | −6.0 ± 27.6 | −4.8 ± 29.9 | 1.2 (−9.0, 11.5) | |
| Pain | −7.8 ± 24.4 | −12.4 ± 31.2 | −4.6 (−14.8, 5.5) | |
| Genital prolapse | −41.5 ± 31.8 | −41.9 ± 37.3 | −0.4 (−12.7, 11.9) | |
| Mean change in DDI domain scores | ||||
| DDI | Constipation | −0.3 ± 17.8 | −2.4 ± 16.8 | −2.1 (−8.4, 4.2) |
| Obstructive defecation | 2.1 ± 18.4 | −5.2 ± 19.1 | −7.3 (−14.2, 0.5) | |
| Pain | −5.8 ± 17.6 | −0.8 ± 19.6 | 5.0 (−1.5, 11.7) | |
| Fecal incontinence | 4.5 ± 20.5 | 1.3 ± 26.5 | −3.2 (−11.7, 5.3) | |
| Flatus | 2.2 ± 37.8 | 2.0 ± 36.0 | −0.2 (−13.2, 12.8) | |
| Mean change in IIQ scores | ||||
| IIQ | Physical | −10.6 ± 26.4 | −13.5 ± 26.4 | −2.9 (−12.4, 6.5) |
| Mobility | −5.6 ± 24.3 | −9.3 ± 22.9 | −3.7 (−11.8, 4.6) | |
| Social | −5.0 ± 19.6 | −8.4 ± 22.6 | −3.4 (−11.2, 4.6) | |
| Embarrassment | −0.9 ± 20.6 | −0.5 ± 23.4 | 0.4 (−7.6, 8.4) | |
| Emotional | −3.6 ± 25.4 | −4.8 ± 24.3 | −1.2 (−10.0, 7.6) | |
| Mean change in PISQ-12 scores | 0.0 ± 4.2 | 2.9 ± 6.8 | −2.9 (−6.8, 1.1) | |
Data presented as mean (domain baseline scores minus corresponding 7-year domain scores) ± standard deviation (SD). Negative scores in change reflect reduction in bother and improved quality of life compared with baseline
UDI Urogenital Distress Inventory, DDI Defecatory Distress Inventory, IIQ Incontinence Impact Questionnaire (0–00), PISQ-12 Prolapse and Incontinence Sexual Questionnaire short form (positive change from baseline indicates better sexual function).