Table 2.
Differentially expressed miRNAs between lamb (L) and adult (A) group
| miRNA | L_readcount | A_readcount | Log2 Fold Change | P-Value | P-Adj | |
|---|---|---|---|---|---|---|
| Higher in lambs than in adults | novel_138 | 38.47793421 | 4.012949941 | 3.2613 | 1.57E-09 | 6.13E-09 |
| oar-miR-1185-5p | 6.231432649 | 1.036267065 | 2.5882 | 0.0043264 | 0.0030268 | |
| novel_469 | 12.13489516 | 2.072534129 | 2.5497 | 7.34E-05 | 5.96E-05 | |
| oar-miR-323c | 10.49504446 | 2.072534129 | 2.3402 | 0.0003234 | 0.00024917 | |
| oar-miR-544-5p | 17.36640855 | 3.835180153 | 2.1789 | 3.24E-05 | 1.71E-05 | |
| oar-miR-541-5p | 6.733913519 | 1.534072061 | 2.1341 | 0.010229 | 0.0040858 | |
| oar-miR-3959-3p | 47.84622764 | 11.50554046 | 2.0561 | 1.48E-11 | 1.01E-11 | |
| novel_468 | 11.47895488 | 2.763378839 | 2.0545 | 0.00030638 | 0.00023908 | |
| oar-miR-376b-3p | 14.88549304 | 4.218698169 | 1.819 | 0.00033006 | 0.00016095 | |
| oar-miR-411b-5p | 63.79497018 | 18.79238275 | 1.7633 | 2.11E-13 | 1.49E-13 | |
| oar-miR-495-5p | 6.379497018 | 1.917590077 | 1.7341 | 0.021096 | 0.0080829 | |
| oar-miR-487a-3p | 8.527223625 | 2.763378839 | 1.6256 | 0.0040362 | 0.0028566 | |
| oar-miR-3955-5p | 64.61011747 | 22.45245307 | 1.5249 | 9.87E-15 | 1.25E-14 | |
| oar-miR-376c-3p | 58.47872267 | 21.86052687 | 1.4196 | 1.22E-10 | 7.90E-11 | |
| oar-miR-376e-5p | 7.08833002 | 2.684626107 | 1.4007 | 0.025836 | 0.009647 | |
| oar-miR-412-3p | 31.18865209 | 11.88905848 | 1.3914 | 3.13E-06 | 1.68E-06 | |
| oar-miR-758-3p | 24.10032207 | 9.587950383 | 1.3298 | 5.76E-05 | 2.96E-05 | |
| oar-miR-432 | 102.7807853 | 41.41994566 | 1.3112 | 1.47E-16 | 1.17E-16 | |
| oar-miR-433-3p | 17.72082505 | 7.286842291 | 1.2821 | 0.00067931 | 0.00031883 | |
| oar-miR-487b-3p | 84.70554374 | 35.28365741 | 1.2635 | 1.53E-13 | 1.11E-13 | |
| oar-miR-410-3p | 53.16247515 | 22.24404489 | 1.257 | 5.30E-09 | 3.16E-09 | |
| oar-miR-379-5p | 4381.651202 | 1882.306419 | 1.219 | 0.00000001 | 0 | |
| oar-miR-127 | 8086.012471 | 3631.532087 | 1.1549 | 0.00000001 | 0 | |
| oar-miR-380-3p | 124.4001919 | 56.76066627 | 1.132 | 1.18E-17 | 1.01E-17 | |
| oar-miR-409-5p | 124.7546084 | 57.91122032 | 1.1072 | 2.07E-17 | 1.69E-17 | |
| oar-miR-382-3p | 183.233331 | 85.90803543 | 1.0928 | 1.39E-24 | 1.37E-24 | |
| oar-miR-106a | 13.11880558 | 6.217602388 | 1.0772 | 0.0019904 | 0.0014596 | |
| oar-miR-539-3p | 42.17556362 | 20.70997283 | 1.0261 | 1.70E-06 | 9.38E-07 | |
| Lower in lambs than in adults | oar-miR-30c | 2721.564311 | 5467.432827 | −1.0064 | 1.96E-16 | 1.53E-16 |
| oar-miR-191 | 3111.422462 | 6305.803208 | −1.0191 | 2.54E-20 | 2.27E-20 | |
| oar-miR-22-3p | 1979.061742 | 4076.796503 | −1.0426 | 1.09E-15 | 8.36E-16 | |
| oar-let-7c | 5531.378331 | 11,531.23617 | −1.0598 | 4.75E-46 | 6.14E-46 | |
| oar-miR-30a-3p | 158.0697595 | 342.8651057 | −1.1171 | 0.0042634 | 0.0018614 | |
| oar-miR-133 | 240.2943877 | 534.6241134 | −1.1537 | 9.94E-05 | 5.04E-05 | |
| oar-miR-218a | 1060.327461 | 2385.141361 | −1.1696 | 3.87E-05 | 3.23E-05 | |
| oar-let-7b | 14,204.65894 | 32,174.86038 | −1.1796 | 1.20E-228 | 3.47E-228 | |
| novel_96 | 31.10489768 | 73.83412387 | −1.2471 | 0.00010598 | 0.00044248 | |
| oar-let-7a | 26,886.7446 | 64,467.46079 | −1.2617 | 0.00000001 | 0 | |
| oar-miR-99a | 33,958.41705 | 81,484.92216 | −1.2628 | 0.00000001 | 0 | |
| oar-miR-200c | 4132.423757 | 10,505.33008 | −1.3461 | 4.02E-55 | 9.06E-55 | |
| oar-miR-26a | 56,450.87634 | 144,854.2462 | −1.3595 | 0.00000001 | 0 | |
| oar-miR-26b | 5129.780951 | 13,523.97604 | −1.3986 | 3.61E-89 | 9.15E-89 | |
| oar-miR-125b | 5760.685808 | 15,940.92631 | −1.4684 | 3.36E-278 | 1.15E-277 | |
| oar-miR-29b | 101.0087028 | 342.8651057 | −1.7632 | 3.74E-12 | 2.60E-12 | |
| oar-miR-148a | 67,574.96753 | 231,061.6487 | −1.7737 | 0.00000001 | 0 | |
| oar-miR-136 | 19.75893919 | 88.81995869 | −2.1684 | 6.98E-10 | 2.81E-09 | |
| oar-miR-150 | 50.50740147 | 235.578046 | −2.2216 | 3.78E-11 | 4.18E-11 | |
| oar-miR-29a | 867.6115945 | 5480.855957 | −2.6593 | 0.00000001 | 0 | |
| novel_459 | 0 | 20.61202625 | −5.3654 | 3.82E-06 | 1.82E-05 |
The DE miRNAs in boldface were validated with qRT-PCR