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. 2018 May 12;17:68. doi: 10.1186/s12933-018-0713-0

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Hif1a mutation and maternal diabetes exposure alter the expression of metabolic genes in the LV myocardium. Relative mRNA expression levels of Cd36 (a) and Ldha (b) in the LV myocardium of 12-week-old offspring by RT-qPCR, the values are mean ± SEM (n = 8). Data are normalized to Hprt1 mRNA of control gene. Statistical significance assessed by two-way ANOVA: genotype effect (Cd36 mRNA, P = 0.0118; Ldha, P = 0.0034); and diabetes effect (Cd36 mRNA, P = 0.0061) with post hoc Tukey’s multiple-comparison test, *P < 0.05, **P < 0.01