Table 2.
Recovery and precision of metronidazole in tablets (n = 6).
| Samples 1 | Detected (μM) |
Spiked (μM) |
Found (μM) |
Recovery (%) |
RSD (%) |
Pharmacopoeia Method 2 (mg/tablet) |
|---|---|---|---|---|---|---|
| Tablet 1# | 22.94 ± 0.23 | 15 | 38.39 ± 0.33 | 103.0 | 0.44 | 22.98 ± 0.26 |
| 30 | 52.61 ± 0.45 | 98.9 | 0.50 | |||
| 45 | 65.49 ± 0.96 | 94.6 | 1.13 | |||
| Tablet 2# | 23.95 ± 0.36 | 15 | 39.60 ± 0.81 | 104.4 | 1.02 | 23.87 ± 0.40 |
| 30 | 53.63 ± 1.29 | 98.9 | 1.20 | |||
| 45 | 65.72 ± 1.44 | 92.8 | 1.54 |
1 Tablet 1#: batch No. 140602, expiry date: 06/2016, from Jilin Wantong Pharmaceutical Group Zhengzhou Wantong pharmaceutical Co., Ltd., Zhengzhou, China; Tablet 2#: batch No. 150201, expiry date: January 2018, from Great Medicine (China) Co., Ltd., Wuhan, China. 2 UV-vis method.