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. Author manuscript; available in PMC: 2018 May 12.
Published in final edited form as: Eur J Cancer. 2014 May 15;50(11):1982–1992. doi: 10.1016/j.ejca.2014.04.017

Fig. 1.

Fig. 1

Scatter plot showing percentage control inhibition of 500 screened compounds. Compounds at two different concentrations 5 and 10 μM were screened for percentage inhibition relative to DMSO control (100% activity or 0% inhibition) minus background [(TBS/HbBSA) (for any auto refolding)]. The Z-factor (z = 0.81 ± 0.17) of the optimised assay reveals its high reliability, sensitivity and reproducibility.