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. Author manuscript; available in PMC: 2019 May 9.
Published in final edited form as: Cell Host Microbe. 2018 May 9;23(5):594–606.e7. doi: 10.1016/j.chom.2018.04.001

Figure 7. Alpha-Toxin Production Is Higher in iNOS-Deficient Mice and Dependent on AgrA Cysteine Residues during Staphylococcal Pneumonia.

Figure 7

Alpha-toxin levels in mouse lungs (top) and bacterial burden (bottom) at 8h post-infection. Mice were infected with ~5 × 107 CFU of wild-type S. aureus Newman, agrA C55S C199S (nitric oxide-resistant mutant), or ΔagrA (null). Alpha-toxin measurements were determined on lung homogenates by ELISA.

Individual values are plotted with horizontal lines showing medians of groups, Mann-Whitney U test, *p<0.05 (n = 20).

See also Figure S7.