(a) Upregulated genes in DBMSCs after preconditioning
Gene | Functions |
---|---|
ATOX1 | Prosurvival, plays a significant role in carcinogenesis [52] |
CYGB | Protective function during oxidative stress [45] |
DHCR24 | Proproliferative, protects neuronal cells from apoptotic cell death [53] |
DUOX1 | Proproliferative, plays a role in cellular migration [54] |
DUOX2 | Proproliferative, plays a role in esophageal, stomach, and colon cancer progression [48] |
DUSP1 | Involved in proliferation and differentiation in various human cancers [55] |
FOXM1 | Execution of mitosis, cell cycle progression, and other signal pathways leading to tumorigenesis [57] |
GCLM | Plays antiapoptotic roles in ovarian follicles [56] |
MBL2 | Prosurvival, used for protection against oxidative stress in neurons [46] |
OXR1 | Plays a role in the etiology of glioma [51] |
OXSR1 | Prosurvival, protection against oxidative stress damage [47] |
PRDX4 | Oncogenic, highly expressed in a majority of human GBMs as well as in a mouse model of GBM [50] |
TXNRD1 | Overexpressed in many malignancies including lung cancer [49] |