. Author manuscript; available in PMC: 2019 Jun 5.

Published in final edited form as: J Pharm Biomed Anal. 2018 Apr 5;155:241–246. doi: 10.1016/j.jpba.2018.04.002

Table 6.

Results of nested case-control study of time-matched participants with and without recurrent parasitemia

Characteristic	Cases n = 9	Controls n = 9	P value
Age, mos., mean (SD)	27 (16)	34 (17)	0.32
Female gender, n (%)	6 (67)	5 (56)	0.96
Weight, kg, mean (SD)	11.4 (2.6)	12 (2.9)	0.54
Net use, n (%)	9 (100)	9 (100)	-
Household indoor residual spraying, n (%)	9 (100)	9 (100)	-
Fever on presentation, n (%)	2 (22)	1 (11)	0.66
Anti-malarial use within prior 1 mo., n (%)	2(22)	1 (11)	0.66
Parasite density at enrollment, μL⁻¹, median (IQR)	9,920 (1,640–18,480)	17,040 (3,640–32,360)	0.21
Time to clearance, h, mean (SD)	26 (13)	35 (11)	0.10
Day 7 lumefantrine concentration, ng/ml, mean (SD)	181 (158)	235 (276)	0.64

P values were estimated from chi-squared or Student’s t test. For parasite density at enrollment, the log-transformed data were used for statistical testing.

SD, standard deviation. IQR, interquartile range.