Table 2. Levels of NK Cell Activity according to Physical Activity Level and Metabolic Factors.
| Variables | Total | Men | Women | ||||||
|---|---|---|---|---|---|---|---|---|---|
| n | NK cell activity median (IQR), pg/mL | p value | n | NK cell activity median (IQR), pg/mL | p value | n | NK cell activity median (IQR), pg/mL | p value | |
| Physical activity level | |||||||||
| Inactive | 4807 | 1461 (637–2651) | <0.001 | 2373 | 1700 (726–2821) | 0.535 | 2434 | 1264 (562–2469) | 0.034 |
| Minimally active | 5940 | 1592 (708–2758) | 3981 | 1726 (782–2810) | 1959 | 1362 (596–2596) | |||
| HEPA | 1267 | 1712 (691–2803) | 865 | 1835 (740–2862) | 402 | 1432 (593–2586) | |||
| Body mass index (kg/m2)* | |||||||||
| <18.5 (underweight) | 528 | 1099 (423–2254) | <0.001 | 74 | 1339 (472–2383) | 0.080 | 454 | 1024 (418–2217) | <0.001 |
| 18.5–27.5 (normal or overweight) | 10134 | 1572 (689–2742) | 6055 | 1723 (767–2817) | 4079 | 1356 (603–2543) | |||
| ≥27.5 (obese) | 1343 | 1648 (703–2787) | 1087 | 1757 (765–2844) | 256 | 1119 (510–2381) | |||
| Waist circumference (cm)† | |||||||||
| ≤90 in men, ≤80 in women | 9119 | 1546 (679–2722) | 0.827 | 6997 | 1723 (768–2811) | 0.783 | 4504 | 1341 (585–2529) | 0.238 |
| >90 in men, >80 in women | 2889 | 1553 (657–2747) | 221 | 1741 (735–2835) | 286 | 1249 (548–2420) | |||
| Fasting blood glucose‡ | |||||||||
| <100 mg/dL | 9372 | 1553 (689–2719) | 0.537 | 5106 | 1741 (797–2817) | 0.066 | 4266 | 1341 (592–2533) | 0.002 |
| ≥100 mg/dL | 2630 | 1517 (623–2749) | 2105 | 1675 (673–2823) | 525 | 1138 (449–2274) | |||
| Hemoglobin A1c‡ | |||||||||
| <6.5% | 11753 | 1555 (679–2730) | 0.006 | 7010 | 1731 (767–2822) | 0.021 | 4743 | 1329 (585–2523) | 0.002 |
| ≥6.5% | 249 | 1261 (476–2522) | 201 | 1450 (498–2530) | 48 | 679 (343–1381) | |||
| Blood pressure‡ | |||||||||
| <130/85 mm Hg | 10823 | 1554 (681–2732) | 0.156 | 6168 | 1755 (794–2837) | <0.001 | 4655 | 1315 (578–2506) | 0.360 |
| ≥130/85 mm Hg | 1179 | 1498 (631–2678) | 1044 | 1510 (632–2658) | 135 | 1453 (605–2744) | |||
| Triglyceride‡ | |||||||||
| <150 mg/dL | 9562 | 1539 (666–2725) | 0.255 | 5079 | 1750 (763–2844) | 0.085 | 4486 | 1329 (589–2426) | 0.046 |
| ≥150 mg/dL | 2440 | 1575 (709–2742) | 2135 | 1656 (752–2760) | 305 | 1215 (459–2253) | |||
| HDL–C (mg/dL)‡ | |||||||||
| <40 in men, <50 in women | 1308 | 1426 (624–2615) | 0.014 | 835 | 1611 (689–2796) | 0.245 | 473 | 1157 (504–2075) | 0.003 |
| ≥40 in men, ≥50 in women | 10694 | 1571 (684–2740) | 6376 | 1738 (768–2822) | 4318 | 1343 (588–2551) | |||
NK, natural killer; IQR, interquartile range; HEPA, health-enhancing physically active; HDL-C, high-density lipoprotein cholesterol.
*Missing values for 9 individuals, †Missing values for 6 individuals, ‡Missing values for 12 individuals.