Table 4.
Log(NT-proBNP) and cognitive function in the CARDIA brain magnetic resonance imaging sample.
| Dependent variable | βa | 95% CI | p-Value |
|---|---|---|---|
| DSST | |||
| Model 1 | −0.12 | −0.22, −0.028 | 0.01 |
| Model 2 | −0.12 | −0.21, −0.031 | 0.01 |
| STROOP | |||
| Model 1 | 0.087 | −0.0001, 0.17 | 0.05 |
| Model 2 | 0.07 | −0.018, 0.16 | 0.12 |
| Rey Auditory–Verbal Learning Test | |||
| Model 1 | −0.004 | −0.099, 0.09 | 0.93 |
| Model 2 | −0.01 | −0.106, 0.08 | 0.83 |
Model 1: adjusted for age, sex, and race.
Model 2: Model 1 covariates + smoking status, anti-hypertension medication use, systolic blood pressure, diastolic blood pressure, cardiovascular history, renal history, body mass index, total cholesterol, glomerular filtration rate, education, and exam center.
aCoefficient indicates the difference in z-scores of the cognitive scores; lower scores on the Digit Symbol Substitution Test (DSST), the Rey Auditory–Verbal Learning Test, and the composite score and higher scores on the STROOP test indicate poorer cognitive functioning.