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. 2018 May 7;9:959. doi: 10.3389/fimmu.2018.00959

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Copyright © 2018 Zhi, Xie and Skare.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bacterial load of Borrelia burgdorferi in C57BL/6 and C1qα^−/− mice. Quantitative PCR (qPCR) from mice infected with 10⁴ B. burgdorferi strain (ML23/pBBE22luc) following 10 days (A) or 21 days (B). White circles and red squares indicate the data points from samples of C57BL/6 and C1qα^−/− knockout mice, respectively [n = 3–4 for panel (A); n = 9 for panel (B)]. Abbreviations: SK, skin; LN, lymph node; JT, joints; HT, heart. The results are represented as the number of borrelial genome copies per 10⁶ mouse β-actin copies (*P < 0.05 and **P < 0.01).