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. 2018 May 7;9:987. doi: 10.3389/fimmu.2018.00987

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Copyright © 2018 Ma, Sun, Sun, Chen, Wei, Yu, Liu, Li and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gamma-aminobutyric acid (GABA) reduces the expression of occludin and junctional adhesion molecule 1 (JAM-1) in mice. (A) Representative immunohistochemical data for occludin staining (brown) in colon mucosa within the different groups, scale bar 100 μm. (B) Representative immunohistochemical data for JAM-1 staining (brown) in colon mucosa within the different groups, scale bar 100 μm. (C) Representative immunofluorescence staining of JAM-1 (red) in DSS-treated Caco-2 cells with or without GABA, scale bar 25 μm.