FIGURE 5.

The macrophage depletion by LEC protected against renal injury and fibrosis in hypertensive DS rats. (A) Representative images of kidney section stained with periodic acid-Schiff (PAS) for evaluation of glomerular injury. (B) Quantitative assessment of glomerular sclerosis in each group of mice. (C) Representative images of kidney section stained with PAS for evaluation of glomerular injury. (D) Quantitative assessment of glomerular sclerosis in each group of mice. NS, DS rats were fed a normal salt diet; HS, DS rats were fed a HS diet; HS/LEC, DS rats were fed a HS diet with LEC treatment. N = 8, ^∗p < 0.05, vs. NS group, ^#p < 0.05, vs. HS group.