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. 2018 May 7;9:473. doi: 10.3389/fphys.2018.00473

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Copyright © 2018 Huang, Wang, Hao, Li, Liu, Yang, Zheng and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of LEC treatment on NADPH oxidative activity (A), the protein expression of renal NADPH oxidase subunits gp91phox (B) and p22phox (C), and phospho-eNOS (Ser 1177, D) in Ang II mice. The macrophage depletion by LEC reduced renal NADPH oxidase activity and the expression of NADPH subunits gp91phox and p22phox, and preserved phospho-eNOS (Ser 1177) in the Ang II mice. N = 8, ^∗p < 0.05, vs. control group, ^#p < 0.05, vs. Ang II group.