Table 2. Multivariate analysis of DFS and OS among patients with tumor size ≤1 cm.
| Predictor | DFS | OS | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Sex (female vs. male) | 2.93 | 0.36–23.90 | 0.316 | 3.52 | 0.26–47.59 | 0.343 | |
| Age (>75 vs. ≤75 years) | 0.78 | 0.06–9.46 | 0.843 | 0 | – | 0.989 | |
| Visceral pleural invasion (yes vs. no) | 7.74 | 0.61–98.12 | 0.114 | 12.22 | 0.83–180.80 | 0.069 | |
| Lymphovascular invasion (yes vs. no) | 4.09 | – | 0.999 | 0.38 | – | 0.999 | |
| Adjuvant chemotherapy (yes vs. no) | 0 | – | 0.980 | 0 | – | 0.973 | |
| Histology (SOL/MIP vs. LEP/ACN/PAP) | 0 | – | 0.997 | 0 | – | 0.998 | |
| Surgical procedure | 0.393 | 0.656 | |||||
| Segmentectomy vs. wedge resection | 0 | – | 0.991 | 0.27 | 0.02–4.34 | 0.359 | |
| Lobectomy vs. wedge resection | 0.23 | 0.03–1.90 | 0.172 | 0 | – | 0.989 | |
HR, hazard ratio; CI, confidence interval; ACT, adjuvant chemotherapy; LEP, lepidic; ACN, acinar; PAP, papillary; MIP, micropapillary; SOL, solid; DFS, disease-free survival; OS, overall survival.