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. 2018 May 7;9:996. doi: 10.3389/fimmu.2018.00996

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Copyright © 2018 Calise, Marquez Renteria, Gregersen and Diamond.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interferon regulatory factor 5 activation does not affect FcγRIIb expression in B cells. (A,B) FcγRIIb mRNA expression in B cells treated with CpG (right) or R848 (left) for the indicated times. Results are combined (A) and separated by haplotype (B). (C,D) FcγRIIb protein expression in B cells treated with CpG (right) or R848 (left) for the indicated time. Results are combined (C) and separated by haplotype (D). All unstimulated cell expression values are normalized to 1.0. p < 0.05, p < 0.01, p < 0.001, and p < 0.0001 by Friedman test with Dunn’s multiple comparisons test (A,C), p = ns by Mann–Whitney test for each treatment (B,D).

Interferon regulatory factor 5 activation does not affect FcγRIIb expression in B cells. (A,B) FcγRIIb mRNA expression in B cells treated with CpG (right) or R848 (left) for the indicated times. Results are combined (A) and separated by haplotype (B). (C,D) FcγRIIb protein expression in B cells treated with CpG (right) or R848 (left) for the indicated time. Results are combined (C) and separated by haplotype (D). All unstimulated cell expression values are normalized to 1.0. p < 0.05, p < 0.01, p < 0.001, and p < 0.0001 by Friedman test with Dunn’s multiple comparisons test (A,C), p = ns by Mann–Whitney test for each treatment (B,D).